Senior researcher at Division of Risk Assessment in National Institute of Health Sciences
Shihori Tanabe, Ph.D. is a senior researcher at Division of Risk Assessment in National Institute of Health Sciences. She completed her doctorate in pharmaceutical science with the field in molecular biology and pharmacology at the University of Tokyo. She also performed the research mainly focused on biochemistry and cellular biology in Department of Pharmacology, College of Medicine, University of Illinois at Chicago. A part of her research is focused on gene expression profiling, cellular signaling network analysis and protein regulation mechanism to find essential factors demonstrating cellular phenotypes in cancer and stem cells using bioinformatics approach including microarray and database analysis. She has also conducted research such as cellular signaling, cardiac cell research and protein regulation mechanism, and made contribution in the field of molecular biology, pharmacology and biochemistry. She has performed research in molecular signaling pathway network mechanism of cellular phenotypes including epithelial-mesenchymal transition and cancer stem cells.
She is interested in finding essential factors to distinguish cancer and stem cell types for revealing mechanism of cancer development and safe application of the cells as cellular therapeutics in regenerative medicine, as well as in assessing the long-term influences of the alteration in gene expression and cellular phenotype from the point of view of regulatory science. She is a delegate for the Japanese Society for Regenerative Medicine, a councilor for Society for Regulatory Science of Medical Products, and an editorial board member for Journal of Toxicological Sciences, Fundamental Toxicological Sciences, World Journal of Stem Cells, World Journal of Gastrointestinal Oncology, and Journal of Medical Genomics and Biomarkers.