Dr Seema Sehrawat
Associate Professor, Vascular Biologist, Dept. of Life Sciences, School of Natural Sciences, Shiv Nadar University, India and Visiting Faculty at Harvard Medical School, Boston, USA
Senior Scientist and Associate Professor with 12 years of research experience post PhD. Currently placed as a Visiting faculty at Harvard Medical School and Associate Professor at Shiv Nadar University, one of the premier private universities in India. Extensive research experience working at Department of Microbiology and Cell Biology, Indian Institute of Science, bangalore followed by Post Doctoral Research fellowship at Harvard Medical School. Publications in high impact journals like Blood, PNAS, Molecular Biology of the Cell, Journal of Immunology, Biochemical Journal, Stem Cell Reports, Gene etc. As a Research Fellow at the highly prestigious Brigham and WomenÃ¢â¬â¢s hospital, Harvard Medical School, I did extensive research work on cAMP mediated Endothelial Cell barrier regulation, extremely relevant mechanism for progression of disease pathogenesis like Breast Cancer, Cerebral Edema, High Altitude pulmonary edema etc.
Cerebral malaria infection and Primary Endothelial Cells
Malaria mediated adhesion and proteomics studies on brain endothelial cells. ECIS based Vascular Permeability Analysis, Cell Migration and Angiogenesis analysis in Human Umbilical Vein Endothelial Cells, Human Brain Endothelial Cells, Human Pulmonary Endothelial Cells, Human Dermal Microvascular Endothelial Cells, Brain Pericytes, Cell Adhesion and Cell Spreading Assays, Gene Silencing and Antisense analysis, Knockdown Analysis using RT-PCR and Western Blot, FACS analysis, In vitro Assay for Apoptosis, ELISA based assays, Flow based assay to mimic physiological setting, Pull down assay, Surface Plasmon Resonance based Protein-Protein interaction analysis. Modulation of primary cell behavior in presence of chemicals, natural products and peptides, Microtubule Dynamics.