Department of Biochemistry, Biophysics and Structural Biology,Institut de Biologie Intégrative de la Cellule (I2BC), Yvette cedex, France.
My area of expertise is the biochemistry of membrane proteins. My scientific interests have mostly been focused on energy-transducing systems and in particular those evolved in organelles. I completed my Ph.D on the biogenesis and regulation of the photosynthetic complexes combining multidisciplinary approaches (I.B.P.C., Paris). Then, I joined the
C.N.R.S. (French National Center for Scientific Research) where I have acquired an excellent appreciation of the mitochondrial system through the study of the biogenesis of respiratory complexes in yeast and human using various biochemical and genetic approaches. I have then chosen to focus my research on the mitochondrial proteome and phosphoproteome study. In this context, I participated in the development of new tools combining biochemical and mass spectrometry analyses. Finally these last years, I have developed a research project with my group on the regulation of OXPHOS complexes by the post-translational modifications and particularly, phosphorylation.
Proteomics, phosphoproteomics, post-translation modifications, membrane proteins, mitochondria, respiratory
complexes, OXPHOS, photosynthetic complexes