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Structural Biology 2018
Volume: 4
Biochemistry & Molecular Biology Journal
Page 59
March 15-16 2018
Barcelona, Spain
10th Edition of International Conference on
Structural Biology
Synthetic biology is the engineering of biology which enables
a rational, bottom-up approach to design and construct
artificial biological systems as well as the redesign of existing
natural biological systems. Structural biology is the elucidation
of molecular mechanisms of natural and artificial biological
architectures, ideally at atomic resolution. Structural biology has
drawn immense benefit from engineering and design, notably for
the recombinant synthesis of biological specimens as objects
of study. Recombinant technology relies on the delivery of
customized, active biological circuits comprising of functionally
arranged synthetic genetic material and regulatory elements
into a variety of natural and engineered host organisms as the
chassis. Synthetic biology approaches hold enormous promise to
decisively advance structural biology in academic and industrial
research and development programs, by accelerating all steps
of circuit design, assembly and delivery, and enhancing available
chassis by targeted engineering. Recent developments, their
applications and potential for investigating the structure and
function of complex multiprotein assemblies will be discussed.
Synthetic biology meets structural biology: from protein
complex structures to synthetic viral nanosystems
Imre Berger
University of Bristol, UK
Biochem Mol biol J, Volume 4
DOI: 10.21767/2471-8084-C1-009