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Page 45

Biochemistry & Molecular Biology Journal

ISSN: 2471-8084

Internat i ona l Conference on

Biotechnology, Biomarkers

& Systems Biology

M a r c h 0 4 - 0 5 , 2 0 1 9

Am s t e r d a m , N e t h e r l a n d s

Biotechnology, Biomarkers & Systems Biology 2019

Hussam N. Fakhouri et al., Biochem Mol biol J 2019, Volume:5

DOI: 10.21767/2471-8084-C1-024

C

onsiderable researches has been devoted to study tumor biomarkers

digital images. Information gathered from studying these images are good

source for automating clinical diagnosis of tumors. This research investigate

the techniques used for analyzing Microscopic images that contain tumor

biomarkers in term of diagnosis and also presents an automated method

for analyzing epithelial dysplasia microscopic biomarker digital images to

provide a clinical diagnosis epithelial dysplasia tumor biomarkers based on

both applying the adaptive threshold and the mathematical calculations of

processing the tumor biomarkers images. 100 tumor marker digital images

for both normal and epithelial dysplasia cases have been experimented.

we preprocess the digital images to enhance them, after that we apply the

adaptive threshold. We achieved a novel finding for determining the value of the

window size for epithelial dysplasia images. We also propose a mathematical

method that can be used for processing of epithelial dysplasia images for the

clinical diagnosis of these

خهال

markers to determine if it is normal or contain

epithelial dysplasia. The results showed that 94% of epithelial dysplasia tumor

biomarkers were correctly diagnosed.

Biography

Hussam N. Fakhouri is a Instructor at the University of Jordan,

Amman Jordan he also responsible for the quality assurance in

the Facluty. His first published research was in year 2006 about

Genome image processing after that he published more than

30 researches in different fields. He studied a PhD in artificial

intelligence. He also was an Erasmus scholar to attend many

research courses in Denmark, Germany and Russia.

h.fakhouri@ju.edu.jo

Clinical Diagnosis Based on Tumor Biomarkers Analysis using

Digital Image Processing and Digital biomarkers Detectors

Case study: Epithelial Dysplasia Cancer

Hussam N. Fakhouri, Faten Hamad and Amal Akour

The University of Jordan, Amman, Jordan