Page 53
Biochemistry & Molecular Biology Journal
ISSN: 2471-8084
Internat i ona l Conference on
Biotechnology, Biomarkers
& Systems Biology
M a r c h 0 4 - 0 5 , 2 0 1 9
Am s t e r d a m , N e t h e r l a n d s
Biotechnology, Biomarkers & Systems Biology 2019
B
acterial pathogens are associated with numerous plant diseases and can account for major economic losses to agricultural
production. Currently, the plant disease management involving the use of traditional chemicals or antibiotics are losing their
efficacy due to the natural development of bacterial resistance to these agents. Bacterial outbreaks are generally problematic
to control due to lack of effective bactericides and to resistance development. Most effective plant disease management
approaches require an integrated strategy utilizing cultural practices, and biological control agents. In this regard, bacteriophages
(also called phages) offer an alternative to conventional management strategies for controlling bacterial plant diseases. Phages
are viruses that specifically infect bacteria yet have no direct negative effects on animals or plants. Infection of a bacterium by a
virulent phage typically results in rapid viral replication, followed by the lysis of the bacterium and the release of progeny phages.
Therefore, phages can be used effectively as part of integrated disease management strategies. A suitable phage candidate for
effective biocontrol should have a sufficiently broad host range against a wide variety of strains, which is known as a polyvalent
bacteriophage. The relative ease of preparing phage treatments and low cost of production of these agents make them good
candidates for widespread in crop protection. Phages have potential for use in integrated disease management strategies, which
the phages provided additional reduction in disease and resulted in more efficient foliar disease control than copper-macozeb.
lalr@bioteksa.comBacteriophages as biotechnological tool against
bacterial plant pathogens
Luis Alberto Lightbourn Rojas
Instituto de Investigación Lightbourn, Mexico
Biochem Mol biol J 2019, Volume:5
DOI: 10.21767/2471-8084-C1-024




