The unsaturated fatty acids for scar tissue modulation

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Abstract

Scar tissue ussualy generates serious discomfort in the short and long term. Anaesthetics sequelae, pruritus, joints malfunction, new wounds on the surface of the scar and pain are common symptoms.There are several treatments for scars, like compression, topical or intralesional infiltration steroids, 5-fluorouracil, dermabrasion, surgeries with new scar tissue. For adult patients, it is easier to choose the treatment. However in children, compression is for regular use, trying to avoid treatments that involve adverse effects. This is a report about four patients, 2 adult woman before abdominoplasty and two post burn scar treatments, who showed significant changes after the continuous use of a ointment composed of Petrolatum, Cod Liver Oil as Active Ingredients; BHT, Chamomilla Recutita (Chamomile) Oil, Helianthus Annuus (Sunflower) Oil and Prunus Amygdalus Dulcis (Sweet Almond) Oil. Unsaturated fatty acids alter cutaneous structural and immunological status since they constitute the stratum corneum, and they can alter the permeability of the skin. They also interfere with maturation and differentiation of the stratum corneum and inhibit production of proinflammatory eicosanoids, reactive species (ROS and RNS), and cytokines, thus influencing the inflammatory response and possibly wound healing. This presentation aims to share the experience in adult and pediatric patients, in a period of three months, with the regular use of an ointment that could increase proinflammatory cytokine production at wound sites with a noninvasive, therapeutical and effective cutaneous wound healing and scarring modulation. This physiopatological explanation, could be the cause of a nimble improvement in scars.

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