Evaluation of diuretic activity of aqueous and ethanolic extracts of Lawsonia inermis leaves in rats

Lawsonia inermis commonly known as henna is a perennial herbaceous plant belonging to family Lythraceae. Traditionally it has been used to treat skin diseases, dysentery, bronchitis, anemia and inflammation. The aim of present study was to investigate the diuretic activity of aqueous and ethanolic extracts of Lawsonia inermis leaves in rats. Aqueous and Ethanolic extracts were administered orally at a dose of 250mg/kg and 500mg/kg. The results were analysed by One Way Analysis Of Variance (ANOVA) .The results showed that both the extracts of leaves showed significant diuresis relatively ethanolic extract has shown more activity than aqueous extract. The findings concluded that Lawsonia inermis leaves exhibit diuresis and further studies are suggested to isolate the active principles responsible for the activity.

Author(s): Chandra Kalyan Reddy. Y*, Sandya. L, Sandeep. D, Ruth Salomi. K, Nagarjuna. S, and Padmanabha Reddy. Y

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