Avena sativa belongs grasses family, the gramineae, commonly known as oat and are the third leading crop produced in United States after wheat and corn and the fourth most important crop worldwide. They are the most widely grown plant generally considered healthy food being commercially nutritious as well. Oat grain, oat bran, and oatmeal contain a soluble dietary fiber known as β-glucan, which can reduce serum concentration of total cholesterol and low–density lipoprotein cholesterol and also effective in lowering blood sugar levels. Various experimental studies have shown that oat is potential agent to prevent the induction and progression of various diseases such as cancer, bowel, malfunction, obesity, celiac disease etc. This review will discuss functional and medicinal properties of Avena sativa. However, owing to the numerous health benefits that they offer, their consumption has increased to quite an extent and they have now come to the forefront.