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Ann Biol Sci, 2017
ISSN: 2348-1927
August 23-24, 2017 | Toronto, Canada
Annual Conference on
MICROBIAL PATHOGENESIS, INFECTIOUS DISEASE,
ANTIMICROBIALS AND DRUG RESISTANCE
I
nfectious diseases caused by bacterial pathogens have
been a serious threat to public health for decades and
remain one of the major concerns of our society. Control and
prevention of pathogen contamination are effective ways to
reduce the risk of such disease. Photo-activated antimicrobial
technology is a rapidly developing field in response to the
demand in development of effective treatments, control and
prevention of bacterial infectious diseases. While colloidal
TiO2 has been the traditional photo-activated antimicrobial
agent for years, novel materials are discovered and added
to this field rapidly. Recently, carbon dots have been
demonstrated for their great potential in serving as effective
light-activated antimicrobial agents. Carbon dots (CDots) are
generally small carbon nanoparticles with various surface
passivation schemes, with their unique optical properties
and photocatalytic functions. This study reported CDot’s
photoinduced bactericidal functions, with the results
suggestingthatthedotswerehighlyeffectiveinbacteria-killing
with visible light illumination. Several important factors that
are associated with the light-activated bactericidal efficiency,
including surface modification, fluorescence quantum yield
and others have been investigated. Mechanistic implications
of the results will be discussed. Challenges and opportunities
in further development of CDots into a new class of effective,
low cost, low to non-toxicity visible/natural light-responsive
bactericidal agents for bacteria control and other potential
antimicrobial applications will be discussed.
e:
lyang@NCCU.EDUCarbon dots: A new class of light-activated antimicrobial agents
Liju Yang
1
and
Ya-Ping Sun
2
1
North Carolina Central University, USA
2
Clemson University, USA
Arch Clin Microbiol, 8:5
DOI: 10.4172/1989-8436-C1-003