endocrinology-2018-posters-abstracts

Endocrinology 2018

Journal of Clinical and Molecular Endocrinology

ISSN: 2572-5432

Page 54

August 09-10, 2018

Madrid, Spain

International Conference on

Endocrinology and

Diabetology

Background:

Hypogonadism complicating diabetes was

predominately hypogonadotropic reflecting pituitary dysfunction.

We evaluated the relationship between vitamin D status with

testosterone deficiency among patients with type 2 diabetes

mellitus (T2DM).

Results:

Testosterone deficiency prevalence in T2DM patients

was 41.1%. Hypogonadismdiabetic patients had significant lower

25(OH)D levels than patients without hypogonadism. Diabetic

patients with testosterone deficiency had significant higher

prevalence of vitamin D deficiency (61.5% and 28.6%), and non-

significant higher prevalence of insufficiency (84.6% and 82.1%)

in comparison with patients without. Vitamin D deficient diabetic

patients showed significant lower total testosterone levels but not

gonadotropin as compared to those without deficiency. In linear

regression analysis, we found that 25(OH)D was a significant

predictor of total testosterone levels in diabetic patients. As per

logistic regression analysis, vitamin D deficiency was found to

be a significant risk factor for male hypogonadism in diabetic

patients.

Conclusions:

Diabetic patients with testosterone deficiency had

significant lower 25(OH)D levels and higher prevalence of vitamin

D deficiency and insufficiency as compared to those without

testosterone deficiency. Vitamin D deficient patients had lower

testosterone levels. 25(OH)D was a significant predictor of total

testosterone levels. Vitamin D deficiency was a significant risk

factor for male hypogonadism in diabetic patients.

25-hydroxyvitamin D status correlation with male

hypogonadism among type 2 diabetic patients

Aboelnaga M Mohamed, Abdullah N

and

E L Shaer M

Mansoura University, Egypt

J Clin Mol Endocrinol 2018, Volume 3

DOI: 10.21767/2572-5432-C2-006