In vitro study of antibacterial activity of Carissa carandas leaf extracts

In the present study we focus on the need for the alternative sources of the antibiotics as the pathogenic microbes are gaining resistance against standard antibiotics. Cold Aqueous, Methanol, Ethanol, Ethyl Acetate extracts of leaves of Carissa carandas in a final concentration of 500 mg/ml were evaluated for their antibacterial properties against some selected pathogenic microorganisms such as Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli using agar well diffusion method. Methanolic, Ethyl Acetate and Ethanolic extracts of Carissa carandas leaves show an average inhibitory zone diameter of 23.5, 22.0 and 21.5 mm respectively which indicate that the Methanolic extract has shown the best result having Zone of Inhibition greater than that of the standard antibiotic Tetracycline (17.0 mm).

Author(s): Tarun Agarwal*, Rachana Singh, Amar Deep Shukla and Imran Waris

Abstract | PDF

Share This Article