In vitro antidiabetic activity of anthocyanin extract of Asystasia gangetica (Chinese violet) flower

The main aim of the present study was to investigate the alpha amylase and alpha glucosidase inhibitory effects of extracted anthocyanins from Asystasia gangetica flower. The plant anthocyanins were isolated with ethanol acidified with citric acid. Different concentrations of anthocyanin extracts were evaluated for alpha amylase and alpha glucosidase inhibition activity. Percentage of alpha amylase and alphaglucosidase inhibitory activity was calculated. In this study the anthocyanin extraction showed significant inhibition activity,at the concentration of 400mmg/ml the plant showed appreciable alpha amylase and alpha glucosidase inhibitory activity (71.46 ± 1.21 %, 76.85 ± 0.75 %) with IC50 value of 260mg/ml and 244mg/ml respectively. In this study we concluded that the crude anthocyanin extract of Asystasia gangetica is a potential source of natural antidiabetic agent. In vitro antidiabetic activity of anthocyanins present in this plant might be due to the presence of anthocyanin phenolic compounds.

Author(s): Kavitha Sama, Rajeshwari Sivaraj* and Rajiv. P

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