Diabetes mellitus is a common and very prevalent disease affecting the citizens of both developed and developing countries. It is estimated that 25% of the world population is affected. Many secondary metabolites of plant are commercially important and find use in a number of pharmaceutical compounds. Syzygium cumini is one of the most popular plants in the world used frequently in history for its medicinal property. It is need of hour to search for alternative drugs for the most popular plants in the world and has been used frequently in history for its medicinal properties. In the absence of reliable Antidiabetic and antihyperlipidemic drugs in allopathic medical practice, herbs play important role in the management of as Antidiabetic and antihyperlipidemic. So, I have studies the Antidiabetic activity of ethanol and aqueous extracts using bark of Syzygium cumini on Albino Westar rats where as Glibenclamide were used as a standard. Biochemical and histopathological evidences indicated that using treatment with the methanol and aqueous extracts of bark of Syzygium cumini effectively protected rats against alloxan induced diabetes.