Journal of Neurodegenerative Diseases and Disorders

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Neuroendocrine Regulation

Neuroendocrine regulation in the hypothalamus and pituitary is responsible for receiving and appropriately integrating signals that control production of its hormonal output signals relate to menstrual cyclicity, sex drive, child birth, and milk production for lactation. The neurons of the neuroendocrine system are large; they are mini factories for producing secretory products; their nerve terminals are large and organised in coherent terminal fields; their output can often be measured easily in the blood; and what these neurons do and what stimuli they respond to are readily open to hypothesis and experiment. The stress response is the complex process that can be initiated by immune or central nervous system. The central nervous system reacts against macroscopic threats and controls whole body response. Thus, in face of lacking of the system integrity central nervous system switches all functions over to subordinate constitutive activities to defense against the threat. The hypothalamus – pituitary – adrenal axis is activated and vasopressin, prolactin and growth hormone are released.

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