Kidney Cancer or Renal Cancer initiated from its cells and defiend as Renal Cell Carcinoma (RCC) and Transitional Cell carcinoma. Significant novel research in molecular medicine defined RCC a common prototype "solid organ" malignancy for specific medical cancer treatment. These novel properties have find ways to possible long life of patients with such metastatic disease. RCC is the most significant renal neoplasia, and after that TCC. Certain biological therapies are available in form of Anti-VEGF Kinase inhibitor but providing conflicting results. Our Journal specially focus on flexibility of Research or review where scientific findings present their text in details to nurture the scientific community in the domain of cancer biology and therapeutic oncology.