Xen45 implant: clinical outcomes

Joint Event on 23rd Edition of Advancements in Ophthalmology: Clinical & Surgical Practices & 24th Edition of International Conference on Ophthalmology Case Reports
July 30-August 01, 2018 Barcelona, Spain

Hassan F, Alfahad Q, Thomson L and Toor G

Warwick Hospital, UK

ScientificTracks Abstracts: Insights in Ophthalmology

Abstract

Purpose of the Study: To report clinical outcomes following Xen45 Gel Stent implantation surgery in patients suffering with primary open angle glaucoma. Methods: A retrospective analysis was performed on all patients who had Xen45 implantation surgery during a 2-year period (Jun 2016–Apr 2018). 53 patients were included with a total of 58 eyes being operated on. Patient’s were followed up for a 6-month period after the operation looking at several parameters including intraocular pressure, number of anti-glaucoma medications required and any stent/bleb complications. Results: There was a 90% (n=52) improvement in intraocular pressure. 83% (n=48) patients had a reduction in the number of anti-glaucoma medications they required to keep an optimal intraocular pressure. Visual field data was available for 31 out of 58 eyes; there was an improvement in roughly half of these cases (55%, n=17). There were very low rates of post-operative infection (2%, n=1) and hypotony (5%, n=3). Several stent complications were reported (48% of patients, n=28) and bleb complications were also reported primarily due to needling (48%, n=28). Conclusions: The Xen45 stent is a promising new device with potentially wide applications. It is a much less invasive procedure than trabeculectomy and clearly has a substantial effect on both intraocular pressure as well as the number of anti-glaucoma medications required. Several complications have been reported, however, overall outcomes remain positive. Further prospective analysis is now required to follow these patients over a 24-month period.

Biography

Hassan F qualified from Brighton and Sussex Medical School and is a Junior Doctor working in Warwick Hospital. He has a specialist interest in Corneal Surgery and Paediatric Ophthalmology.

E-mail: faaiq1@hotmail.co.uk