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PCOS 2018
Journal of Clinical and Molecular Endocrinology
ISSN: 2572-5432
Page 35
June 07-08, 2018
London, UK
4
th
World Congress on
Polycystic Ovarian
Syndrome
Purpose:
Endometriosis and ovarian varicesmanifest with similar
symptomologies and the hormone estradiol is implicated in both.
We decided to investigate the possible association between them.
Materials & Methods:
The sample consisted of 48 female
patients between the ages of 18 and 50 years old. There were
25 patients who had been diagnosed with endometriosis; 15
had been confirmed by surgery and histopathology and 10 by
nuclear magnetic resonance. There were also 23 patients without
endometriosis who were considered to be the control group. The
study design was an observational case control type.
Results:
The prevalence of ovarian varices in patients with
endometriosis was 80%, whereas, the control group was only
26.1%. The elevated percentage of ovarian varices in patients
with endometriosis is highly significant, with a difference of
53.9% and 95% confidence interval of 30% to 78%. The criteria for
the determination of significance that we adopted was the level
of 5%. The statistical analysis was processed using the statistical
software SAS system, version 6.11 (SAS Institute, Inc., Cary, North
Carolina).
Conclusion:
Our results suggest that ovarian varices play a very
important role in the physiopathology of endometriosis. Ovarian
varices may evolve with oxidative stress in the function of the
ovary, provoking an imbalance in its genetic, hormonal, and
immunological aspects, provoking the chronic inflammatory
process particular to endometriosis.
kennedy-gp@uol.com.brThe prevalence of ovarian varices in patients with endometriosis
Kennedy Gonçalves Pacheco
Brazil
J Clin Mol Endocrinol 2018, Volume 3
DOI: 10.21767/2572-5432-C1-003