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PCOS 2018
Journal of Clinical and Molecular Endocrinology
ISSN: 2572-5432
Page 32
June 07-08, 2018
London, UK
4
th
World Congress on
Polycystic Ovarian
Syndrome
Aim:
To investigate and discus the clinical curative effect of
laparoscopic sleeve gastrectomy (LSG) on polycystic ovary
syndrome (PCOS) .
Methods:
A retrospective analysis for the clinical data of 21
patients with PCOS accepted LSG in the Tenth People’s Hospital
Affiliated to Tongji University from May 2013 to July 2017 was
made to compare the changes of menstrual cycle, body weight,
endocrine and inflammatory factors before and after 6 months
operation.
Results:
6 months after the operation, 90% patients recovered
their normal menstrual cycle and ovulation. The shortest recovery
period was two days and the average was (1.89 ± 1.286) months,
and 1 patient recovered the fertility. The clinical data of 10 patients
showed that canthosis nigricans were recovered, fasting blood
glucose, glycosylated hemoglobin FBG, fasting insulin HbA1C
FINSandHOMA-IRwere significantly decreased (P<0.001), insulin
sensitivity index IAI increased significantly (P<0.001), triglyceride
TG decreased significantly (P<0.01), HDL increased significantly
(P<0.001), uric acid UA significantly decreased(P<0.001)and
testosterone T level decreased significantly (P<0.001).
Conclusion:
LSG can decreased significantly improve the clinical
symptoms of patients with PCOS which may be independent of
weight and the change of Endocrinology and metabolism, and the
mechanism needs to be further discussed. Metabolic surgery can
be used as the effective treatment of patients with PCOS. Early
improvement from metabolic surgery for patients with obese
polycystic ovary syndrome may be independent of the benefits
of weight loss.
Biography
Jie Dai is a postgraduate of Tongji University, resident physician, works
in Youyi Community Health Center, Shanghai, China. She was selected in
Baoshan medical personnel training program in the year 2015 and Tutor
Shen Qu MD, PhD, professor, major in endocrine and metabolic diseases.
251634656@qq.comEarly improvement in metabolic surgery for obese polycystic
ovary syndrome may be independent of the benefits of weight loss
Jie Dai
and
Shen Qu
Tongji University, Shanghai, China
Jie Dai et al., J Clin Mol Endocrinol 2018, Volume 3
DOI: 10.21767/2572-5432-C1-003