Electrochemical NanoBiosensor Applications Devoted to Clinical Analysis

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Abstract

 Electrochemical biosensors provide sensitive, fast response, low cost, miniaturized and easy to handle systems to obtain excellent point of care (POC) platforms1. In recent years, a prompt development of nanotechnology and a better understanding of nanoparticle structures and properties have enabled their use in different areas of biosensors for diagnosis and monitoring of not only diseases but also drug discovery, food analysis and quality control2. Among all nanomaterials, graphene oxide (GO) is one of the most attributed materials for opening new possibilities in the development of next generation biosensors due to its unique properties, such as high electron transfer rate, high affinity for specific biomolecules, thermal stability, water solubility, large specific surface area, exceptional elasticity and rigidity3. On the other hand, transition metal oxide nanoparticles of iron, titanium, manganese, zirconium, cobalt, nickel and their composites offer promising features in the field of electrochemical and biosensing.Transition metal oxide nanoparticles of different shapes and structures have been synthesized using various techniques. These metal oxide nanoparticles possess good electrical and photocatalytic properties because of their size, shape, stability and larger surface area.

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