Abstract

Synthesis, structural study and biological evaluation of 1,3-thiazine

The acid base catalysed aldol condensation of 2-hydroxy acetophenone with substituted benzaldehyde and anisaldehyde furnish substituted chalcone which were later treated with diphenyl thiourea and dinitro diphenyl thiourea in ethanol in presence of aqueous potassium hydroxide solution.The reaction mixture was refluxed for 3 hours ,cooled diluted with water and acidified with 1:1 HCl afforded substituted 1,3- Thiazines.


Author(s): Reshal Deshmukh

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