ISSN : 0976-8505
Der Chemica Sinica
Abstract
Synthesis and antimicrobial screening of some thiazolidine derivatives of isoniazid
Some new N-(4-oxo-2-alkyl/aryl-thiazolidine-3-3yl) isonicotinamide derivatives of isoniazid have been synthesized and evaluated for their Anti-bacterial, Antifungal and Anti-tubercular activity. Synthesized compounds show significant activity against bacterial, fungal and mycobacterium strains. Their structures were established on the basis of elemental analysis, IR, 1H NMR and Mass Spectral data.
Author(s): Rakesh Patel and Anil Bhandari
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