Synthesis and antimicrobial activity of some naphthyl ether derivatives

The main objective of this work is to synthesize naphthyl ethers in the micellar catalyzed medium, which is advantageous over the conventional method of preparation. The compounds prepared show, promising activity as therapeutic agents. In the present work, the substituted Phenacyl naphthyl ethers have been synthesized by electrophilic substitution on substituted naphtholate ion with 4-methyl phenacyl bromide or 4-chloro phenacyl bromide. The compounds have been characterized by physical data and further screened for anti-microbial activities

Author(s): M.I. Fazal Mohamed1, Arunadevi.S2 , M.Koperuncholan3 and M. Seeni Mubarak4

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