Semicarbazone analogues: A mini review

Semicarbazones are compounds which are synthesized by the condensation of semicarbazide and aldehydes/ketones. The literature survey revealed that semicarbazones had been emerged as a compound with broad range of activities including anticonvulsant, antitubercular, anticancer and antimicrobial activity. Dimmock et al., reported an extensive series of semicarbazones and reported 4-(4-fluorophenoxy) benzaldehyde semicarbazone as potential anticonvulsant. Preclinical evaluations have been completed and an IND has been filed for this potential compound. In the present study we have focused on the biological activity of semicarbazone analogues.

Author(s): Mohamed Jawed Ahsana, Jeyabalan Govinda Samy, Habibullah Khalilullah and Md. Shivli Nomani

Abstract | PDF

Share This Article