Relationship between contributor/beneficiary MTRR quality polymorphisms and the danger of new-beginning neurological intricacies after liver transplantation

Liver transplantation (LT) is one of the best options for the treatment of end-stage liver disease. At present, because of the high survival rate, many complications associated with LT patients are increasing. NCs are one of them. It is reported that up to 30% of the patients in western countries developed neurological complications after LT, but only 4% after heart transplantation and 0.5% after renal transplantation (Agildere et al., 2006, Amodio et al., 2007, Bronster et al., 2000, M et al., 2006). Frequent complications include acute confusion, epilepsy, cerebrovascular disease (Otan et al., 2015a, Otan et al., 2015b), and central system infection (Weiss and Thabut, 2019). These symptoms lead to a decline in the quality of life of patients, and even increase the mortality rate (Ghaus et al., 2001). Early and accurate identification of NCs high-risk patients is helpful to prevent disease and improve the prognosis of recipients.Since there is no accepted model or indicator for the prediction of NCs before, our research has practical guiding significance.

Author(s): Haojun Wang Qingdao University, China

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