Occupational Exposure to Pesticide: A Risk of Diabetic Neuropathy

Prevalence of diabetic neuropathy is increasing at high speed despite of significant progress in its pathogenesis and its etiologies suggesting the requirement of a nontraditional risk factor for the development of diabetic neuropathy. Environmental chemicals could be one of the reasons behind the development of diabetic neuropathy as many environmental chemicals are known to be positively associated with hyperglycemia and diabetes. Therefore, in this mini-review, we have listed some of the epidemiological studies which show the occurrence of diabetes on pesticide exposure. We have also listed epidemiological studies where exposures of different classes of pesticides are known to induce neuropathy in the exposed population. This study provides substantial evidence that exposure to pesticides might lead to development of diabetic neuropathy. Although, at present, there are no studies available which suggests exposure to pesticide may induce diabetic neuropathy. Therefore, future studies in this direction will be helpful in evaluating as well as elucidating the mechanism behind pesticide-induced diabetic neuropathy

Author(s): Himanshu Pawan Kumar Gupta, Rukmani Pandey and Shabana Anjum

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