Ultrasonics has become an important and powerful research tool in physics. The ultrasonic study of liquid mixtures has been gaining importance in assessing the nature of molecular interactions and understanding the physicochemical behaviour of liquid. In present investigation, ultrasonic velocity, density, viscosity has been measured in liquid mixture of linoleic acid (9, 12-Octadecadienoic acid) and α-tocopherol (Vitamin E) with different compositions using ethanol as solvent. The measurements are done at 2MHz frequency and in temperature range 293K to 313K using pulse echo technique. Thermo acoustical parameters viz., adiabatic compressibility, relaxation time, free length, acoustic impedance, and internal pressure have been computed from the experimental data. The variation of ultrasonic velocity and other thermo-acoustical parameters shows nonlinear increase or decrease with variation in composition. The nature of solute-solute and solute-solvent interactions and effect of composition on molecular interactions have been studied.