Virus is one of the major constraints of pepper production. Increasing outbreaks of virus species infecting Hot Pepper (Capsicum annuum L.) is a major problem for pepper growers due to a combination of factors, including expansion of pepper cultivation and abundance of insect vectors. Many viruses have been identified to infect pepper crops causing economic loss in terms of reduced quality and marketable yield, sometimes up to 90%-100%. Potato virus Y (PVY), Tobacco etch virus (TEV) and Cucumber mosaic virus (CMV) are the most severe pepper virus around the world. The management options for virus infection in Capsicum annuum is by the integration of several approaches. More significantly, removing of infected plants, cultivation of disease resistant varieties, improved cultural practices and using of insecticides especially when plants are young and easily colonized by vectors. However, integrated management measures are needful to reduce occurrence of virus diseases in Capsicum annuum.