Abstract

In the present study, to investigates its chemical stability and the in vitro sun protection factor (SPF) of Carica papaya L fruit extract in a gel formulation. Due to its antioxidant and photo protective properties, Carica papaya L is a promising candidate for use in cosmetic and pharmaceutical formulations. A high performance liquid chromatography method was used to evaluate the chemical stability using Carica papaya L extract as marker at 5, 25 and 45 ◦C for 103 days. The sun protection factors were analyzed by ultraviolet (UV) spectrophotometry using samples irradiated with UVB lamp. The chemical stability of the Carica papaya L extract gel was determined according to the concentration of Carica papaya L extracts at different storage temperatures (5, 25 and 45 ◦C) for 103 days. It is screened for In vitro sun protection factor in the Carica papaya L extract and of its gel formulation and determinesPhoto stability of the isolated Carica papaya L extract and SPF. This study has shown that the Carica papaya L fruit extract gel is stable for at least 2 to 3 months when stored at 5 and 25oC. This proved activity of plant showed its importance and prophylactic utility in anti- solar formulation. This will be a better, cheaper and safe alternative to harmful chemical sunscreens that used now a day in the industry.
Author(s): Sachin G. Lokapure, Shubhangi D. Salunkhe, Punam N. Shenekar, Sumaiyya T. Sutar, Prachi S. Ukirade, S. K. Mohite and C. S. Magdum

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