Abstract

In vitro evaluation of SPF, photostability and chemical stability of Carica papaya L. fruit extract gel

In the present study, to investigates its chemical stability and the in vitro sun protection factor (SPF) of Carica papaya L fruit extract in a gel formulation. Due to its antioxidant and photo protective properties, Carica papaya L is a promising candidate for use in cosmetic and pharmaceutical formulations. A high performance liquid chromatography method was used to evaluate the chemical stability using Carica papaya L extract as marker at 5, 25 and 45 ◦C for 103 days. The sun protection factors were analyzed by ultraviolet (UV) spectrophotometry using samples irradiated with UVB lamp. The chemical stability of the Carica papaya L extract gel was determined according to the concentration of Carica papaya L extracts at different storage temperatures (5, 25 and 45 ◦C) for 103 days. It is screened for In vitro sun protection factor in the Carica papaya L extract and of its gel formulation and determinesPhoto stability of the isolated Carica papaya L extract and SPF. This study has shown that the Carica papaya L fruit extract gel is stable for at least 2 to 3 months when stored at 5 and 25oC. This proved activity of plant showed its importance and prophylactic utility in anti- solar formulation. This will be a better, cheaper and safe alternative to harmful chemical sunscreens that used now a day in the industry.
Author(s): Sachin G. Lokapure, Shubhangi D. Salunkhe, Punam N. Shenekar, Sumaiyya T. Sutar, Prachi S. Ukirade, S. K. Mohite and C. S. Magdum

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