Formulation and evaluation of antistress polyherbal capsule

The most important challenges faced by herbal formulations arise because of their lack of complete evaluation. So evaluation is necessary to ensure the quality and purity of the herbal product. For evaluation of capsule containing poly herbal crude drugs various parameters were tested. The aim of present study was to formulate and evaluate the polyherbal capsule and evaluate it for parameter of raw material include physicochemical studies like ash values and extractive values. Preformulation parameters and parameters for finished product (hard gelatin capsule) include uniformity of weight, disintegration time and other quality control test were performed. HPTLC and DSC was done for marker compounds, individual drugs and finished product. Data of HPTLC studies suggests that extract was derived from genuine plant parts. DSC thermo gram suggested that there was no interaction between the crude drugs and excipients. Future prospects include the clinical trials of the finished product as the clinical efficacy is already proven in different animal studies.

Author(s): Mohd. Nayeemullah Khan, J Suresh, K S Hemant Yadav and J Ahuja

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