Distinct anti-microbial effects of synthesized ZnS, Ag-N co-doped ZnS and ZnS-Fe2O3 composite nanoparticles against some pathogenic bacterial strains

ZnS, Ag-N co-doped and ZnS/Fe2O3 composite nanoparticles were synthesized by chemical and sol-gel methods. As-synthesized nanomaterial have been characterized by XRD and TEM techniques and their antimicrobial effects were studied by paper disc diffusion technique against gram positive (Staphylococcus aureus and Streptococcus) as well as gram negative (Pseudomonas aeruginosa and Escherichia coli) bacteria. Doping of Ag and N into ZnS showed enhanced antimicrobial activity of ZnS. Synthesized antibiotic material exhibited higher activity against Gram positive bacteria than Gram negative bacteria. Antimicrobial activity of Ag-N co-doped ZnS was also compared with the activity of two commercially available antibiotics- Gentamycin and Azithromycin. Compositing of Fe2O3 with ZnS showed antagonistic effect towards the antimicrobial activity of the later.

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