Density & viscosity studies of Fluoxetine hydrochloride in mixed binary solvent in presence of additives

The densities and viscosities of Fluoxetine hydrochloride are determined in binary solvent ethanol-water containing salt NaCl, KCl, NiCl2, CuCl2 and a non electrolyte Glucose. The values are used to calculate excess viscosities, excess molar volume, excess Gibbs free energy of viscous flow and d12, T12 and H12 parameters. The viscosity results are used to calculate the Jones Dole viscosity B-coefficient. These results indicate that fluoxetine HCl act as structure making compounds due to hydrophobic hydration

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