Biopotency of Allium sativum.Linn (Garlic) in Lead Acetate Intoxicated Male Albino Rats

The present study was undertaken to examine the inhibitory effect of the Bulbs part of Garlic (Allium sativum.L) on Lead acetate induced hepatotoxicity in Liver. Enhanced synthesis of Total cholesterol and decreased synthesis of HDL cholesterol were observed in the liver of Lead acetate poisoned rats. Administration of the Paste of Allium sativum 500 mg/kg body weight effectively suppressed the synthesis of cholesterol in the liver, thus controlling the effect of Lead acetate. The results suggest that Allium sativum may exert a protection effect by inhibiting the synthesis of cholesterol and the vitamins induced by Lead acetate.

Author(s): P.Vinoth Kumar, A.Amala bricey, V.Veera thamarai selvi, C. Sudheer kumar and N.Ramesh

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