Abstract

Analgesic and antipyretic activities of two medicinal plants - Salvinia minima and Dactyloctenium australe in experimental animal models

The present study was conducted to evaluate the possible analgesic and antipyretic effects of aqueous extracts of leaves of Salvinia minima and Dactyloctenium australe. For investigating the analgesic activity, hot plate method maintained at 55°C was used. The extracts of both the plants were found to have significant (p<0.001) analgesic activity at the oral dose of 100, 200 & 200 mg/kg b. wt., in the tested models. In hot plate test, both plants showed increased latency period which are significant (p<0.001) compared to control. Besides, yeast-induced hyperpyrexia was used to evaluate the antipyretic activity. A significant (P < 0.01) reduction in hyperpyrexia in the tested models was observed by the aqueous extract of D. australe. Antipyretic effect of S. minima was also observed but no significant effect was found.


Author(s): Rashed-Al-Qayum, Mohammad Didar Khan, Md. Mizanur Rahman Moghal, Mohammad Nurul Amin, Md. Shohel Hossain and Md. Delowar Hossain

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