Scholarly Journals In Sensitive Biomarker

A  sensitive biomarker" (biological marker) is an indicator of a bodily function that can be objectively measured. A wide range of possible biomarkers for IBS have been considered but at the present only gut, transit measured using radio-isotope markers meet the criteria of reproducibility and availability. While barostat studies perform reasonably in expert centers, to do them reproducibly requires considerable effort and standardization. This makes them unsuitable for widespread use. However radio-isotope tests are expensive and of limited availability so the search for other more convenient markers including blood and stool tests is still an important goal for the future. The development of noninvasive diagnostic tools for discovery of novel lung cancer specific biomarker is emerging as an important to identify early stage of lung cancer and therapeutic applications. Proteomic techniques including two-dimensional gel electrophoresis (2-DE) and differential gel electrophoresis coupled with MS technology are useful for the analysis of tumormarkers . Recently, different proteomic approaches have been used for biomarker discovery in urine samples of lung cancer patients . All of these studies have provided interesting data that contributed to enrich the urinary proteomic map of lung cancer patients.

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