Journal of Molecular and Cellular Biochemistry

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Protein Structure Prediction

Protein prediction is the recognition of a three-dimensional structure of a protein from its amino acid sequence — that is, its prediction of its folding and its secondary structure. The structural prediction differs fundamentally from the opposite problem of protein structure. Protein structure prediction is one of the most important goals followed by bioinformatics and natural chemistry; is of great importance in medicine (for example, in drug development) and in biotechnology (for example, in the production of novel enzymes). Every two years, the effectiveness of current methods is evaluated in the CASP (Critical Protein Testing for Protein Use). Further testing of protein-based web prediction servers is done by the community project CAMEO3D. Protein chains of amino acids are bound together by peptide bonds. Many reactions of this chain are possible due to the rotation of the chain with each C atom.

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