Pharmacogenetics Innovations

Pharmacogenetics is primarily concerned with human DNA variation but there have also been important recent advances in understanding variation in tumor DNA, especially in the design of drugs that target mutated genes within tumors. The current article will focus only on recent developments and current challenges in pharmacogenetics in germline DNA. Targeted therapies where the response depends on tumor genotype are outside the scope of this article but have been reviewed recently elsewhere.

Current pharmacogenetics knowledge can be considered on an individual gene, therapeutic area or individual drug basis. This article will provide a general background on gene families of particular relevance to pharmacogenetics but the emphasis will be on individual drugs.

High Impact List of Articles

The 48 XXYY Syndrome in a Beninese Child: Clinical Features and Genetic Considerations
Simon Azonbakin*, Marius Adjagba, Natacha Nbouke, Diane Adovoekpe, Arnaud Agbanlinsou, Jules Maroufou Alao, Flore Gangbo1 and Anatole Laleye
Case Report: Journal of Genetic Disorders
The 48 XXYY Syndrome in a Beninese Child: Clinical Features and Genetic Considerations
Simon Azonbakin*, Marius Adjagba, Natacha Nbouke, Diane Adovoekpe, Arnaud Agbanlinsou, Jules Maroufou Alao, Flore Gangbo1 and Anatole Laleye
Case Report: Journal of Genetic Disorders
The Mechanism of Cancer Cellular Genome Disorder and Comparison Therapeutic Effects of Modern Methods and New Method Cancer Treatment
Michail Ponizovskiy
Review Article: Journal of Genetic Disorders
The Mechanism of Cancer Cellular Genome Disorder and Comparison Therapeutic Effects of Modern Methods and New Method Cancer Treatment
Michail Ponizovskiy
Review Article: Journal of Genetic Disorders
Cholestasis with Normal Gammaglutamyl Transferasis from Management to Molecular Investigation with Novel Mutations in ATP8B1 and ABCB11: Tunisian Study
Barkaoui E*, Alobaidy H, Darragi I, Ayadi A, and Abbes S
Commentary: Journal of Genetic Disorders
Cholestasis with Normal Gammaglutamyl Transferasis from Management to Molecular Investigation with Novel Mutations in ATP8B1 and ABCB11: Tunisian Study
Barkaoui E*, Alobaidy H, Darragi I, Ayadi A, and Abbes S
Commentary: Journal of Genetic Disorders
Consanguineous Marriage: A Peril for Coming Generation
Munir Ahmad Bhinder
Editorial: Journal of Genetic Disorders
Consanguineous Marriage: A Peril for Coming Generation
Munir Ahmad Bhinder
Editorial: Journal of Genetic Disorders
Lipodystrophy, NAFLD and Pancreatic Neuroendocrine Tumor in a Patient with LIPE Mutation
Jeremy Wang, Jihane N Benhammou, Wayne Grody and Joseph R Pisegna
Case Report: Journal of Genetic Disorders
Lipodystrophy, NAFLD and Pancreatic Neuroendocrine Tumor in a Patient with LIPE Mutation
Jeremy Wang, Jihane N Benhammou, Wayne Grody and Joseph R Pisegna
Case Report: Journal of Genetic Disorders

Conference Proceedings

Mesenchymal stem cell labelling using magnetic particles for in vitro applications
Reem Alkharji and Sottile V
ScientificTracks Abstracts: Journal of Stem Cell Biology and Transplantation
Mesenchymal stem cell labelling using magnetic particles for in vitro applications
Reem Alkharji and Sottile V
ScientificTracks Abstracts: Journal of Stem Cell Biology and Transplantation

Journal of Genetic Disorders