American Journal of Pharmacology and Pharmacotherapeutics

contact@imedpub.com Submit a Manuscript

Open Access Articles On Pharmacophore

The pharmacophore is a logical description of the molecular features that are important for the expression of a ligand molecule by a natural macromolecule. IUPAC describes the pharmacophore as "a meeting point for the steric and electronic features needed to ensure high-quality interactions of a specific biological target and to create (or block) its biological response". The pharmacophore model demonstrates how miscellaneous ligands can interact at a common receptor site. In addition pharmacophore models are used to classify the formation of denovo or virtual screening novel ligands that will connect to the same receptor. The pharmacophore characteristic features are aromatic rings, hydrophobic centimeters, hydrogen bond acceptors or donors, cents and anions. These pharmacophoric points may be located on the ligands themselves or may be speculative points that must be placed on the receptor. The features needed to match different chemical groups with similar structures, to form new ligands. Ligand-receptor interactions are specific to a sequence of positive. The direct pharmacophore model supports both the hydrophobic capacity and the hydrogen bond vectors. In the development of modern drugs, pharmacophores are used to describe the essential properties of single molecules for the same biological function. The data of compound compounds can be viewed by many cells that share the same properties set in the same equations.

High Impact List of Articles
Conference Proceedings

Relevant Topics in Pharmaceutical Sciences

Awards Nomination 17+ Million Readerbase
Google Scholar citation report
Citations : 256

American Journal of Pharmacology and Pharmacotherapeutics received 256 citations as per Google Scholar report

image
Abstracted/Indexed in
  • Google Scholar
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Directory of Research Journal Indexing (DRJI)
  • IndianScience.in
  • Jour Informatics
  • CiteSeerx
  • American Standards for Journals and Research (ASJR)
  • InfoBase Index
  • Secret Search Engine Labs
  • Euro Pub

View More »

Open Access Journals