Macrophagocytic

Any of the massive , mononuclear, highly phagocytic cells derived from monocytes, occurring within the walls of blood vessels and in loose animal tissue. they're components of the RES . Macrophages have their origin within the bone marrow, where they undergo the monoblast and promonocyte stages to the monocyte stage; the monocytes enter the blood then the tissues, where they become macrophages. Macrophages are usually immobile but become actively mobile when stimulated by inflammation. Their functions include phagocytosis and pinocytosis, presentation of antigens to T and B lymphocytes, and secretion of a spread of products, including enzymes, several complement components and coagulation factors, some prostaglandins and leukotrienes, and a number of other regulatory molecules. cf. immunity.

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