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Seasonal variation in the number of patients with profound hyponatremia (<125 mEq/L) at the admission to Matsumoto Medical Center in Japan

9th Edition of International Conference on Preventive Medicine & Public Health
July 16-17, 2018 London, UK

Nobukazu Sasaki, Shoko Kimura and Yuji Aoki

National Hospital Organaization Matsumoto Medical Center, Japan

ScientificTracks Abstracts: J Prev Med

DOI: 10.21767/2572-5483-C1-002


We experienced a case of severe hyponatremia (serum Na level, 104 mEq/L) while treating with a thiazide diuretic for hypertension. Then, we surveyed the frequency of patients with profound hyponatremia (<125 mEq/L) at the admission to Matsumoto Medical Center Matsumoto Hospital from May 2016 to April 2017 during one year prior to the hospital admission of the index patient. The patients with profound hyponatremia were 127 in 4,223 newly admitted patients. Out of 127 patients, 118 patients were aged 65 years or older. Ten patients with severe hyponatremia (<115 mEq/L) were all older than 65 years, in which two patients including the index patient were prescribed a thiazide diuretic. Table 1 shows the frequency of patients with profound hyponatremia each month during the surveillance period. It is of interest that seasonal variation was found in the number of the patients with profound hyponatremia. The frequency was significantly (p=0.013, unpaired t-test) low during the relatively cold period around Matsumoto City in Japan from November to March compared to the other period in the year. Such seasonal variation suggests that the occurrence of profound hyponatremia is to no small extent attibutable to elderly patients’ living environment. This finding is also expected to help healthcare providers in Preventive Medicine and Public Health.


Nobukazu Sasaki is a Resident Physician of National Hospital Organization Matsumoto Medical Center, Matsumoto, Japan. He got his Medical Doctor in 2017 at Shinshu University School of Medicine, Matsumoto, Japan.

E-mail: [email protected]

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