International Journal of Anesthesiology & Pain Medicine

Possible DRESS syndrome in a patient with systemic sclerosis and rheumatoid arthritis during treatment with lamotrigine

Joint Event on 7^th Edition of International Conference on Pain Management & 8^th Edition of International Conference on Internal Medicine & Patient Care
March 25-26, 2019 Rome, Italy

Ivan R Jeremic and Predrag Ostojic

Institute of Rheumatology, Serbia University of Belgrade, Serbia

Posters & Accepted Abstracts: Int J Anesth Pain Med

DOI: 10.21767/2471-982X-C1-006

Abstract

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a severe, potentially life-threatening idiosyncratic drug reaction, usually caused by anti-epileptics, antibiotics or non-steroidal anti-inflammatory drugs, after a latency period of three weeks to three months. Typical clinical features include mucocutaneous rash, fever, lymphadenopathy and internal organ involvement. We report a patient with systemic sclerosis, rheumatoid arthritis and osteoporosis, who developed possible DRESS syndrome to lamotrigine, used to treat epilepsy. Clinical features suggesting DRESS syndrome includes severe rash, fever, lymphocytopenia and thrombocytopenia. The condition was initially unsuccessfully treated as an acute allergic reaction to ibandronate with parenteral glucocorticosteroid and antihistamine. This report aims to increase the awareness of this rare entity in the rheumatology community.

Biography

Ivan Jeremic has completed his Research Master’s Degree in Rheumatology from Belgrade School of Medicine and Clinical medicine PhD candidate at Novi Sad University.

E-mail: ivanjeremic@rocketmail.com