Journal of Clinical and Molecular Endocrinology

Parameters of ovarian reserve in patients with chronic kidney disease depending on glomerular filtration rates.

11^th International Conference on Endocrinology and Diabetology
August 09-10, 2018 Madrid, Spain

Iwona Szydlowska, Aleksandra Marciniak, Agnieszka Brodowska, Marcin Lisak, Sylwia Przysiecka ,Jacek Rozanski.

Posters & Accepted Abstracts: J Clin Mol Endocrinol

DOI: 10.21767/2572-5432-C2-006

Abstract

THE AIM OF THE STUDY was to assess the parameters of ovarian reserve in patients with chronic kidney disease stages 3-4 and compare them between 3 groups of patients with decreased GFR MATERIALS AND METHODS: The examination included 24 patients ages 23 to 45, all with chronic kidney disease stages 3-4. The examined parameters of ovarian reserve included: transvaginal ultrasonography (to assess AFC and ovarian volume), serum AMH, FSH and E2 assessed in early follicular phase of menstrual cycle. All patients included to the study had been diagnosed with CKD (kidney damage or dysfunction) and had decreased GFR below 60 ml/min/1.73 m2 for at least 3 months. Patients were divided depending on the glomerular filtration rates into 3 groups: • with GFR 45-59 ml/min/1,73 m2 • with GFR 30-44 ml/min/1,73 m2 • with GFR 15-29 ml/min/1,73 m2 RESULTS: Parameters of ovarian reserve: ovarian volume, AFC, AMH, FSH; estradiol (E2) depending on estimated glomerular filtration rates (eGFR) ranges in patients with CKD CONCLUSION: There are no significant differences in parameters of ovarian reserve: ovarian volume, AFC, AMH, FSH and E2 among the patients in stage 3 or 4 of chronic kidney disease.

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