Dentistry and Craniofacial Research

Oral and systemic manifestations and its relation to CD4 counts in HIV patients on HAART-an observational study

25^th International Conference on Dental Treatment
September 10-11, 2018 Zurich, Switzerland

Ceena Denny

Manipal Academy of Higher Education, India

Posters & Accepted Abstracts: J Dent Craniofac Res

DOI: 10.21767/2576-392X-C3-009

Abstract

Introduction: Oral and systemic manifestations are common in HIV/ AIDS and are considered to be important predictors of the disease. CD4 count serves as an important marker for the progression of HIV to AIDS. Our objective was to correlate the oral and systemic manifestations associated with HIV infection with CD4 count in patient’s on HAART. Materials & Methods: This was an observational study among one hundred and ten HIV diagnosed patients. The oral and systemic manifestations were noted and compared to their CD4 counts. Chi-square analysis was carried out to see the association of oral manifestations. P<0.05 was considered statistically significant. Results: Among the 110, fifty had CD4 count >500 cells/μL, 46 patients had between CD4 count between 200-499 cells/μL and fourteen had <200 cells/μL. Among patients with CD4 > 500, the oral manifestations observed are as follows, dental caries (n=30, 60%) periodontitis and lipoatrophy (n=25, 50%) and in CD4 count between 200-499, dental caries (n=28, 60.9%) intraoral pigmentation (n=23, 50%), periodontitis (n=20, 43.5%) and with subjects with CD4 count. The most common systemic manifestation observed were tuberculosis (p<0.001) and pneumonia (p<0.003). Clinical Significance: Prevalence of oral and systemic manifestations among HIV infected patients have declined since the advent of highly active antiretroviral therapy (HAART). Oral and general physicians should be able to identify and treat the patients at the earliest, which in turn could reduce the morbidity and mortality rates among those infected with HIV.

Biography

Ceena Denny has completed her Master’s degree in Oral Medicine and Radiology from Bapuji Dental College and Hospital, Davangere in the year 2006 and is currently working in Manipal College of Dental Sciences, affiliated to Manipal Academy of Higher Education as an Associate Professor in the Oral Medicine and Radiology. She has more than 40 publications in various national and international journals and has also presented research papers in national and international conferences. She has authored chapter in text book of Oral Medicine and Radiology published by Elsevier’s science. She frequently conduct lecture in CBCT as a part of certificate programme.

E-mail: ceena.denny@manipal.edu