Liver FDG metabolism and liver enzymes connections

Zerrin Dede

doi:10.21767/2574-285X-C1-003

Liver FDG metabolism and liver enzymes connections

International Conference on Nuclear Medicine & Radiation Therapy
October 01- 02 , 2018 Stockholm , Sweden

Zerrin Dede

University of Katip Celebi, Turkey

Posters & Accepted Abstracts: J. med phys & appl sci 2018

DOI: 10.21767/2574-285X-C1-003

Abstract

Introduction: PET/CT with the radioactively labelled glucose analogue [18F]-fluoro-2-deoxy-2-D-glucose (18F-FDG) can be used to quantify the hepatic metabolic function and visualise regional metabolic heterogeneity. We determined the variation in humans with and without liver disease. Standardised uptake value (SUV) of 18F-FDG from static scans can substitute the hepatic systemic clearance of 18F-FDG from dynamic scans as measure of metabolic function. Patient selection: One year’s all oncological patient applicants to PET CT unit were selected. The correlation between ALT, AST and SUV was samples. whole- SUV, average SUV multiplied by total metabolic liver volume) were calculated. Results: No significant differences were found SUV. SUV had higher with hepatosteotic patients. correlation coefficients metabolic liver enzymes had non-significant variation. Conclusions: The reproducibility of 18F-FDG PET/CT was good and SUV can of hepatic metabolic function. Total SUV of 18F-FDG is a promising tool for quantification of metabolic liver function in hepatosteoz.