Journal of Transmitted Diseases and Immunity

Detection of anal dysplasia with chromoendoscopy and narrow band imaging

Infectious Diseases and STD-AIDS
April 26-27, 2018 Rome, Italy

Michelle D. Inkster and James S. Wu

Digestive Disease and Surgery Institute, United States of America

ScientificTracks Abstracts: J Transm Dis Immun

DOI: 10.21767/2573-0320-C1-002

Abstract

Anal dysplasia precedes anal cancer. High-definition chromoendoscopy with narrow band imaging and acetic acid was used to identify anal squamous intraepithelial lesions (SIL) in patients with abnormal anal cytology. 260 Patients were examined. Demographic characteristics are mean age (range) 47 (21-82) years; MSM (n= 158); HIV positive (n= 161). Associated diagnoses are urogynecologic SIL, solid organ/bone marrow transplantation and inflammatory bowel disease. Lesions were biopsied for histologic diagnosis and then ablated with hot forceps or Gold probeâ�?¢. Results showing comparison of cytology to histopathology are shown in ASCUS = atypical cells of undetermined significance; LSIL = low grade squamous intraepithelial lesion; HSIL â�?�? high grade squamous intraepithelial lesion; SCC = squamous cell carcinoma. These results are for first time chromoendoscopy. Anal transitional zone lesion identification is enhanced by retroflexed inspection during rectal insufflation. Anal canal lesion detection is facilitated by endoscopic inspection through a lighted anoscope. Providers who perform esophagoduodenoscopy and/or colonoscopy routinely should be able to perform anal chromoendoscopy to detect anal SIL since the technique is part of routine gastroendoscopic practice.�? 

Biography

Michelle Inkster completed her PhD in Cell and Molecular Biology at St Louis University before entering Medical School at Case Western University. She is a Staff Gastroenterologist at the Cleveland Clinic in Cleveland Ohio. She is a Fellow of the American College of Gastroenterology. Her interests are improving the detection and treatment of anal dysplasia.
Email:mdinkster@aol.com