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Biological study of some first series transition metal complexes with adenine ligand

Joint Event on 25th Nano Congress for Future Advancements & 12th Edition of International Conference on Nanopharmaceutics and Advanced Drug Delivery
August 16-18, 2018 | Dublin, Ireland

Hamad M I Hasan, Aaza I Yahiya, Safaa S Hassan and Mabrouk M Salama

Omar Al-Mukhtar University, Libya Cairo University, Egypt University of Benghazi, Libya

Posters & Accepted Abstracts: Nano Res Appl

DOI: 10.21767/2471-9838-C3-015


Adenine complexes were prepared with some of the first series transition metals in a stoichiometric ratio of 1:2 ( Mn+: L), where Mn+ = Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+, and Cd2+ ions. The complexes were characterized by the physicochemical and spectroscopic techniques as electric conductivity, metal contents, IR, UV–visible, and molar conductance techniques. The stoichiometric ratios of the synthesized complexes were confirmed by using molar ratio method. The dissociation constant of adenine ligand was determined spectrophotometrically. Solvent effect on the electronic spectra of the adenine ligand was examined using solvents with different polarities. The biological activity of adenine ligand and its metal complexes were tested in vitro against some selected species of fungi and bacteria. The results showed a satisfactory spectrum against the tested organisms.



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