A fatal case of colchicine poisoning of a non-suicidal overdose

Annual Congress on Medicinal Chemistry, Pharmacology and toxicology
July 30 - 31 , 2018 Amsterdam , Netherlands

Seung Hyun Ko and Gun Woo Lee

Catholic University of Daegu, Gyeongbuk, Republic of Korea

Posters & Accepted Abstracts: J Org Inorg Chem

DOI: 10.21767/2472-1123-C3-009

Abstract

Colchicine is a drug widely used on a variety of illnesses for a long time. Colchicine, however, is a drug that has been reported to have adverse effects not only at apparent toxic dose but also at lower and therapeutically recommended dose. Typical therapeutic dose of colchicine is up to 2.4 mg daily, sometimes up to 8-10 mg daily. But in this case, we experienced a case in which the patient showed sudden deterioration and died due to unintentional colchicine poisoning of a relatively small dose. Therefore, when a colchicine poisoned patient visits the hospital, the physician should identify the patient's colchicine poisoning dose and the concomitant drugs. Also the patients should be monitored intensively for 24 or 72 hours and managed as various supportive treatment methods early and actively.

Biography

Seunghyun Ko has graduated from Catholic University of Daegu School of Medicine. After completing his internship, he completed the Residency program in 2013 and became an Emergency Medicine physician. Currently, he is an Assistant Professor at the Department of Emergency Medicine at the Catholic University of Daegu. He has published more than 3 papers in reputed journals and has been serving as an Editorial Board Member of repute.

E-mail: wokay@naver.com

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