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E u r o S c i C o n J o i n t E v e n t s o n
Plant Science, Tissue Engineering
and Parasitology
December 03-04 , 2018
Amsterdam, Nether l ands
International Journal of Applied Science - Research and Review
ISSN: 2394-9988 Plant Science | Tissue Engineering | Parasitology 2018
With the progress of technological advancement, biopolymers have
drawn great attention in the modern regenerative therapy. Scaffold-
based tissue engineering approach is truly promising in repairing and/or
regenerating diseased/damaged tissues/organs. Natural biopolymers mimic
the properties of natural extracellular matrices (ECM) of tissues. However, the
natural biopolymers inherit a number of limitations that include large batch-
to-batch variation, limited resources, poor mechanical performance etc.
Synthetic biopolymers overcome these limitations offering a range of benefits
such as enormous availability, high processability, controllable biomechanical
properties and so on. Because of favourable viscoelastic property and low
melting temperature, PCL has been one of the most contributing biopolymers
to the field of tissue engineering. In this study, a set of polycaprolactone (PCL)-
based biopolymers were employed to develop a scaffold family to cater for
various tissue engineering applications as per necessity. The scaffolds were
fabricated using a customized desktop robot based rapid prototyping (DRBRP)
technique. Morphological and mechano-chemical characterizations were
performed using scanning electron microscope (SEM) and in vitro degradation
test, respectively. The biocompatibilities of the fabricated scaffolds were
also tested via cell culture study. The results demonstrated great potential
of the PCL-based synthetic biopolymers for advanced scaffold-based tissue
engineering therapy.
Biography
Md Enamul Hoque is a Professor in the Department of
Biomedical Engineering at the Military Institute of Science and
Technology (MIST), Dhaka, Bangladesh. Previously, he served
a number of key positions in some other global universities
prior to joining MIST including Head of Department, Biomedical
Engineering at King Faisal University (KFU), Saudi Arabia and
also Founding Head of Bioengineering Division, Department
of Mechanical, Materials and Manufacturing Engineering at
the University of Nottingham Malaysia Campus (UNMC). He
received his PhD from the National University of Singapore
(NUS), Singapore in 2007. He also obtained his PGCHE (Post
Graduate Certificate in Higher Education) from the University
of Nottingham, UK in 2015. He is a Chartered Engineer (C Eng)
certified by the Engineering Council, UK and Fellow of Higher
Education Academy (FHEA), UK. So far, he has authored
three books, edited three books and co-authored 19 book
chapters. He has also published around 160 technical papers
in referred journals and international conference proceedings.
His publications have attracted about 900 citations. His major
research interests include the areas of biomaterials, bio-
composites, tissue engineering, stem cells, rapid prototyping
technology, nanotechnology, nanomaterials.
Polycaprolactone (PCL) based synthetic
biopolymers for modern scaffold-based tissue
engineering
Md Enamul Hoque1, Wahab M A2, Daei J M G 3 and Chuan Y L 4
1Military Institute of Science and Technology (MIST), Bangladesh
2University of Sunshine Coast, Australia
3Technical University of Denmark, Denmark
4Taylor’s University Lakeside Campus, Malaysia
Md Enamul Hoque et al., Int J Appl Sci Res Rev 2018, Volume: 5
DOI: 10.21767/2394-9988-C2-006