plant-science-tissue-engineering-parasitology-2018-posters

12 / 33

Page 54
E u r o S c i C o n J o i n t E v e n t s o n
Plant Science, Tissue Engineering
and Parasitology
December 03-04 , 2018
Amsterdam, Nether l ands
International Journal of Applied Science - Research and Review
ISSN: 2394-9988 Plant Science | Tissue Engineering | Parasitology 2018
Malaria and hepatitis-B co-infection in relation
to selected haematological parameters among
attendees of two health facilities in Port Harcourt,
Nigeria
Wokem G N1 and Amacree M A 2
1Rivers State University, Nigeria
2Braithwaite Memorial Specialist Hospital, Nigeria
Biography
Wokem G N has obtained her PhD from University of Port
Harcourt, Nigeria and postdoctoral studies from Federal
Medical Laboratory Science School, Nigeria. She is an
Associated Professor of Parasitology and Public Health, a
licensed Histopathologist with Medical Laboratory Science
Council of Nigeria (MLSCN), the South Zonal Coordinator of
Parasitology and Public Health of Nigeria (PPSN) and Formal
Head, Department of Medical Laboratory Science, Rivers State
University, Nigeria. She has presented papers in many national
and international conferences with more than 50 papers
published in reputed journals and have been serving as an
Editorial Board Member of repute.
Across-sectional study was conducted among subjects from modern primary
health centre (MPHC), Eneka and Braithwaite Memorial Specialist Hospital
(BMSH) in Port Harcourt, to determine malaria and hepatitis-B co-infection in
relation to selected haematological parameters. 700 subjects of different ages
and both sexes were included in the study after ethical approval was obtained
from Rivers State Ministry of Health, Port Harcourt. Consent forms were issued
to get subjects consent before questionnaires to obtain their demographic data.
The uninfected subjects were used as control. Four milliliters (4 ml) of blood was
taken from each subject by vein-puncture; 2 ml each was dispensed into EDTA
and plain bottles for analysis. The samples were used to assay for full blood
count (FBC), hepatitis-B surface antigen (HBsAg), hepatitis-B envelop antibody
(HBeAb), hepatitis-B core antibody (HBcAb) and hepatitis-B virus (HBV) markers
using standard techniques whereas EDTA bottled blood was for malaria parasite
identification using Giemsa staining technique. The overall prevalence rates of
malaria (27.0%), HBV (5.1%) and co-infection (1.9%) in Port Harcourt were as
stated. The females have higher prevalence of malaria (16.1%) than the males
(10.9%) while the males have higher prevalence of HBV (3.0%) and co-infection
(1.0%) than the female (2.1%) and (0.9%) respectively; although not statistically
significant (P≥ 0.05). The prevalence of malaria was statistically highest among
children 47.7% (6-11) and 48.4% (0-5) years (P≤0.05). HBV was highest among
subjects of age brackets 8.2% (24-29 years) and 9.2% (30-35 years) accordingly.
The packed cell volume was significantly affected by malaria (P≤0.05) but neither
hepatitis-B nor co-infection (P≥0.05). The HBV markers result showed that while
HBsAg occurred among all subjects that were positive for HBV, HBeAb was
completely absent; this is an indication of an on-going or previous infection with
hepatitis-B virus.
Wokem G N et al., Int J Appl Sci Res Rev 2018, Volume: 5
DOI: 10.21767/2394-9988-C2-006