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Page 78
Journal of Infectious Diseases and Treatment
ISSN: 2472-1093
7
t h
E u r o s c i c o n C o n f e r e n c e o n
Clinical Pathology
and Epidemiology
F e b r u a r y 2 7 - 2 8 , 2 0 1 9
P r a g u e , C z e c h R e p u b l i c
Clinical Pathology & Epidemiology 2019
Background:
Group B
Streptococcus
(GBS) causes a significant number of stillbirths. Despite this, there is little documented
information on the association between stillbirth and pregnant women’s GBS recto vaginal colonization in Sub-Saharan Africa. As
such, this study was aimed at identifying the association between stillbirth and pregnant women’s GBS recto vaginal colonization
in Eastern Ethiopia.
Methods:
A health facility-based cross sectional study was conducted among 1688 pregnant women who came for delivery
services in Harar town, Eastern Ethiopia from Jun’ to Oct’ in 2016. Data were collected using a pre-tested structured questionnaire
and check list for clinical record. Group B
streptococcus
(GBS) positivity of the pregnant women was confirmed by culture of recto
vaginal swab using selective media. The association between GBS colonization and stillbirth was examined using multivariable
logistic regression analysis. Level of statistical significance was declared at P value <0.05.
Results:
Of the 1688 pregnant women who participated in the study, 144 had stillbirths, representing a proportion of 8.53% [(95%
CI: 7.19, 9.86]. GBS colonization at birth was detected in 231 (13.68%; 95% CI: 12.04, 15.32). Of these 144 stillbirths, 59 (40.97%)
were from colonized mothers, 72 (59.03%) were from non-colonized mothers. Of these 59 stillbirth from colonized mothers,
32 (54.23%) were intrapartum stillbirth, 27 (45.77%) were antepartum stillbirth occur before exposed to intrapartum antibiotic
prophylaxis (IAP). After controlling for potential confounders, the odds of having a stillbirth was 9.08 times higher among recto
vaginal GBS colonized pregnant women [AOR= 8.93; 95% CI: 5.47, 14.56].
Conclusions:
This study demonstrated significant association between maternal recto vaginal GBS colonization and stillbirth.
Efforts to reduce stillbirth need to consider prevention of GBS colonization among pregnant women.
tesfaye.assb@gmail.comMaternal Group B
Streptococcus
recto vaginal
colonization increases the odds of stillbirth:
evidence from Eastern Ethiopia
Tesfaye Assebe
1
, Alemayehu Worku
2
, Gudina Egata
1
, Berhanu
Seyoum
1
, Dadi Marami
1
and Yemane Berhane
3
1
Haramaya University, Ethiopia
2
Addis Ababa University, Ethiopia
3
Addis Continental Institute of Public Health, Ethiopia
J Infec Dis Treat 2019, Volume: 5
DOI: 10.21767/2472-1093-C1-009